Itraconazole, known as by the names Sporanox®, Intrafungol®, Onmel®, is an antifungal drug used in dogs and cats to inhibits the growth of fungal organisms by interfering with the formation of the fungal cell wall. It is similar in its action to other related drugs, such as miconazole, fluconazole and ketoconazole (Nizoral®).
Itraconazole is classified as a synthetic oral triazole antifungal drug. It can be used to treat skin infections as well as generalized systemic infections.
composition
Each scored tablet contains: Itraconazole 100 mg.
indication
Treatment of fungal infections that affect lungs, nails, mouth, throat, etc. Tinea caused by dermatophytes. Systemic, superficial and deep mycosis. As prophylaxis in patients with immune suppression. Do not administer in pregnant females, lactating animals or in patients with hepatic failure.
Dosage: 1 tablet every 10 to 20 kg/bw (5 to 10 mg/kg). Interval between doses and treatment duration: Pulse therapy: Every 24 hours for two consecutive days, interrupting for 5 days, and repeating the treatment for at least 4 weeks, or until the remission of the symptoms. Daily treatment (systemic mycoses): 1 tablet every 20 kg bw (5 mg / kg), every 24 hours, for not less than 4 weeks or up to signs submission.
Administration: Oral.
precautions
While generally safe and effective when prescribed by a veterinarian, itraconazole can cause side effects in some animals.
Itraconazole should not be used in animals with known hypersensitivity or allergy to the drug.
Itraconazole should not be used in pregnant or nursing dogs or cats.
The most serious adverse effect is that which affects the liver (hepatitis). Signs of decreased appetite, jaundice, vomiting or diarrhea should be reported to your veterinarian.
Itraconazole may interact with other medications. Consult with your veterinarian to determine if other drugs your pet is receiving could interact with itraconazole. Such drugs include antacids, digoxin, cisapride, amphotericin B, various sedative such as diazepam, alprazolam and midazolam), buspirone, corticosteroids, ranitidine, famotidine, omeprazole, ivermectin, phenobarbital, vincristine, vinblastine, clomipramine, amitriptyline, and certain antibiotics.
Compared to some of the other antifungal drugs (amphotericin B, ketoconazole), itraconazole has been associated with fewer adverse effects.
Itraconazole may cause vomiting, diarrhea, weight loss, depression, and decreased appetite in dogs and cats.
| All | |
|---|---|
| Brand | Zoovet |
| Classification | Rx (Prescription Only) |
| Uncategorized | |
| Packing Size | 120 Tabs |